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First Lecture: How does the Human Body manage the Corona Virus?

Mi. 13.01.2021 18:15 Uhr

Wie unser Immunsystem das Corona-Virus kontrolliert

Prof. Dr. med. Percy Knolle

Direktor des Instituts für Institut für Molekulare Immunologie

Jan 13, 2021, 06:15 p.m.

How does the Human Body manage the Corona Virus?

Prof. Dr. med. Percy Knolle

Director of the Institute of Molecular Immunology and Experimental Oncology


How does the Human Body manage the Corona Virus?

The SARS-CoV-2 pandemic poses an unparalleled challenge to societies and health care systems worldwide. SARS-CoV-2 infection in humans starts with infection of cells of the upper respiratory tract. From there, it can spread further down the respiratory tract into the lung but also spread within the entire human body. Because SARS-CoV-2 uses a cellular receptor for infection, which is expressed by many different cell types in the human body, the infection of many different organs can occur. The clinical course of the disease can vary from the infection that is not even noticed by the infected individual (asymptomatic infection) to moderate to severe COVID-19 disease with life-threatening complications. The response of the body´s immune system to viral infection is important for the control of the SARS-CoV-2 infection but is also responsible for causing disease. This lecture will provide insight into how the immune system controls the virus and how deleterious immunity leading to organ damage can arise. The understanding of the immune response to SARS-CoV-2 is important for protection and immunopathogenesis. Monitoring of immune responses to SARS-CoV-2 is therefore important to evaluate protection from infection. Altogether, this lecture will provide a piece of basic knowledge on how the body copes with SARS-CoV-2 infection and what role the immune response to SARS-CoV-2 has during the control of infection but also for protection from further infection.

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Professor Percy Knolle

Prof. Knolle (*1962) erforscht die Mechanismen der lokalen Steuerung von Immunantworten im Gewebe, insbesondere der Leber. Schwerpunkt ist die Regulation von Immunität durch gewebeständige immunkompetente Zellen als Basis für die Entwicklung neuer Immuntherapien.

Prof. Knolle studierte Medizin in Frankfurt, Birmingham, Genf und Straßburg und promovierte am Deutschen Krebsforschungszentrum in Heidelberg. Nach seiner Facharztausbildung für Innere Medizin und Hepatologie am Universitätsklinikum Mainz wurde er 1997 Nachwuchsgruppenleiter am Zentrum für Molekulare Biologie der Universität Heidelberg. Im Jahre 2002 wurde er an an die Universität Bonn auf den Lehrstuhl für Molekulare Medizin berufen und war Gründungsdirektor des Institutes für Molekulare Medizin und Experimentelle Immunologie sowie Ko-Koordinator des Sonderforschungsbereichs 704 und Sprecher des Excellence Clusters ImmunoSensation. 2013 wurde er auf den Lehrstuhl für Molekulare Immunologie an die TUM berufen.

Research Expertise

The focus of Prof. Knolle’s research group is on the molecular and cellular mechanisms governing local immune control in tissues. In his laboratory, the relevance of local antigen presentation by organ-resident liver cells was demonstrated for induction of immune tolerance in naïve CD4 and CD8 T cells. The development of novel cell separation techniques allowed us to study the mechanisms and functional relevance of different liver cell populations at a new level of resolution and to compare the immune function of these non-professional antigen-presenting cells with myeloid professional antigen-presenting cells such as dendritic cells or macrophages. His group has discovered novel stimulatory pathways that are initiated by unique immune sensory mechanisms in liver-resident antigen-presenting cells that trigger local T cell immunity in the liver. The lab has developed an interest in local mechanisms determining the regulation of CD4 T cell differentiation with particular reference to the impact of nuclear receptors that also impact on the metabolic state of T cells.



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Second Lecture: SARS-CoV2: From Discovery to Vaccination


Mi. 20.01.2021 18:15 Uhr

Von der Entdeckung des SARS-Coronavirus-2 zur Impfung

Prof. Dr. med. Ulrike Protzer

Direktorin des Instituts für Virologie

Jan 20, 2021, 06:15 p.m.

SARS-CoV2: From Discovery to Vaccination

Prof. Dr. med. Ulrike Protzer

Director of the Institute of Virology



Professor Ulrike Protzer

Prof. Protzer (*1962) arbeitet auf dem Gebiet der Virus-Wirt Interaktion des Hepatitis B Virus. Der Schwerpunkt ihrer Arbeiten liegt auf dem molekularen und immunologischen Verständnis der Viruskontrolle. Basierend auf diesem Verständnis entwickelt sie mit ihrer Arbeitsgruppe neue Therapieansätze für die Behandlung der chronischen Hepatitis B und deren Folgeerkrankungen.

Nach dem Studium der Humanmedizin an den Universitäten Erlangen, Basel und Durban (Südafrika) promovierte Prof. Protzer 1989 in Erlangen und erwarb 1996 nach gastroenterologischer und infektiologischer Ausbildung in Frankfurt und Mainz die Facharztbezeichnung für Innere Medizin. Nach einer Postdoktorandenzeit am Zentrum für Molekulare Medizin in Heidelberg (1996-2000) habilitierte sie sich 2000 im Fach Virologie und begann eine zweite klinische Ausbildung zum Facharzt für Mikrobiologie, Virologie und Infektionsepidemiologie (2005). Von 2002-2007 leitete sie eine Nachwuchsgruppe am Zentrum für Molekulare Medizin der Universität Köln. Ende 2007 übernahm sie den Lehrstuhl für Virologie an der TUM und ist seitdem Direktorin des Instituts für Virologie an der TUM und am Helmholtz Zentrum München.






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Third Lecture: Distributive Justice in the Pandemic: ICU Triage and Vaccine Allocation


Mi. 27.01.2021 18:15 Uhr

Verteilungsgerechtigkeit in der Pandemie am Beispiel von Triage und Impfung

Prof. Dr. med. Alena Buyx

Direktorin des Instituts für Geschichte und Ethik der Medizin

Jan 27, 2021 06:15 p.m.

Distributive Justice in the Pandemic: ICU Triage and Vaccine Allocation

Prof. Dr. med. Alena Buyx

Director of the Institute of History and Ethics of Medicine 


Distributive Justice in the Pandemic: ICU Triage and Vaccine Allocation

The pandemic has thrown into stark relief the challenge of allocating scarce medical resources fairly, be they lifesaving intensive care treatment or protective vaccines. The lecture will discuss recent frameworks for priority setting and distribution with a focus on issues of ethics and justice, focussing on two cases (triage, and vaccines). It will also discuss the translation of ethical distributive frameworks into practice and policy.


Professor Alena Buyx

Die Arbeitsgebiete von Prof. Dr. med. Alena Buyx reichen von medizinethischen Fragen aus der klinischen Praxis über Herausforderungen durch biotechnologische Innovation und medizinische Forschung bis hin zu ethischen und Gerechtigkeitsfragen in modernen Gesundheitssystemen. Sie verfolgt dabei einen interdisziplinären Ansatz von „embedded ethics“ und kollaboriert mit klinischen Kollegen ebenso wie mit Kollegen verschiedener anderer Fachrichtungen. Alena Buyx ist Mitglied verschiedener nationaler, internationaler und universitärer Gremien, berät regelmäßig große internationale Forschungskonsortien und ist nachgefragte Rednerin und Expertin für Medienauftritte. Seit 2016 ist sie Mitglied des Deutschen Ethikrats und im Jahr 2019 wurde sie in das WHO Expert Advisory Committee on Developing Global Standards for Governance and Oversight of Human Genome Editing aufgenommen.

Professor Alena Buyx ist vollapprobierte Ärztin mit weiteren Abschlüssen in Philosophie und Soziologie. Sie habilitierte sich 2013. Vor ihrer Ernennung in München war sie Professorin für Medizinethik an der Universität Kiel, Emmy Noether-Gruppen-Leiterin an der Universität Münster, Academic Scholar an der Harvard University, stellvertretende Direktorin des englischen Ethikrats und Senior Fellow am University College London.

Mitgliedschaften (Auswahl)


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Fourth Lecture: Dimensions of Psychological Distress in Pandemic


Mi. 03.02.2021 18:15 Uhr

Dimensionen der psychosozialen Belastung in der Pandemie

Prof. Dr. med. Peter Henningsen

Direktor der Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie am Klinikum rechts der Isar

Feb 3, 2021, 06:15 p.m.

Dimensions of Psychological Distress in Pandemic

Prof. Dr. med. Peter Henningsen

Director of Department of Psychosomatic Medicine and Psychotherapy, TUM University Hospital


In this lecture, Professor Henningsen will discuss and present data on the following:

  • Which mental and bodily symptoms are characteristic of psychosocial distress?
  • What are factors that increase vulnerability or resilience for such distress?
  • What are the specific aspects of psychosocial distress in patients with COVID-19, in healthcare workers, family members of patients, people severely affected by lockdown measures, the general public, etc.?
  • What are the consequences of psychosocial distress, e.g., on infection vulnerability?
  • What can be done preventively and therapeutically


Professor Peter Henningsen

Professor Henningsens (*1959) Forschungsgebiet sind anhaltende Körperbeschwerden ohne ausreichende organische Erklärung. Dabei handelt es sich um somatoforme oder funktionelle Störungen wie Schmerzen, Funktionsstörungen, Erschöpfung. Er koordiniert diagnostische und therapeutische Studien, aber auch funktionelle Bildgebungs- und andere psychophysiologische Untersuchungen zu den neurophysiologischen Korrelaten des Beschwerdeerlebens.

Prof. Henningsen hat in Stuttgart-Hohenheim, Freiburg, Berlin und Cambridge (UK) Medizin studiert und zunächst eine Ausbildung zum Neurologen in Berlin und Heidelberg absolviert, bevor er in die Psychosomatische Medizin wechselte. Er habilitierte 2002 in Heidelberg und folgte 2005 dem Ruf an den Lehrstuhl für Psychosomatische Medizin und Psychotherapie. 2006 zum ersten Prodekan ernannt, bekleidete Prof. Henningsen von 2010 bis 2019 das Amt des Dekans der Fakultät für Medizin der TUM. Er ist Mitglied im Medizinausschuss des Wissenschaftsrats, Sprecher der leitenden Hochschullehrer für Psychosomatische Medizin und Vorstandsmitglied der Viktor-von-Weizsäcker-Gesellschaft.




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Fifth Lecture: Effects of the Pandemic on Companies and the Way We Work


Mi. 10.02.2021 18:15 Uhr

Auswirkungen der Pandemie auf Unternehmen und die Arbeit und Zusammenarbeit

Prof. Dr. Isabell M. Welpe

Lehrstuhl für Strategie und Organisation, Fakultät für Wirtschaftswissenschaften

Feb 10, 2021, 06:15 p.m.

Effects of the Pandemic on Companies and the Way We Work                 

Prof. Dr. Isabell M. Welpe

Chair for Strategy and Organization, TUM School of Management


Effects of the Pandemic on Companies and the Way We Work 

Die Pandemie verändert Arbeit und Zusammenarbeit in Unternehmen, die nun verstärkt neue Organisationsformen sowie virtuelle Führung und Teamarbeit einführen. Der Vortrag stellt Highlights der internationalen Managementforschung sowie aktuelle Unternehmensbeispiele zu diesen Themen in den Mittelpunkt.

The pandemic is changing work and collaboration in companies, which are now increasingly introducing new organizational forms as well as virtual leadership and teamwork. The presentation will focus on highlights of international management research as well as current company examples on these topics.


Professor Isabell M. Welpe

Nach dem Studium der Wirtschaftswissenschaften an der Ludwig-Maximilians-Universität München sowie am Massachusetts Institute of Technology in Boston, USA und einem Masterstudium an der London School of Economics, England wurde Prof. Welpe an der Universität Regensburg am Lehrstuhl für Technologie- und Innovationsmanagement promoviert (2003) und an der LMU (Prof. Dr. Dres. h.c. Arnold Picot) zum Thema Innovation und Organisation habilitiert (2007). Seit 2009 ist sie Inhaberin des Lehrstuhls für Strategie und Organisation an der TUM.


Professor Welpe forscht aus einer verhaltenswissenschaftlichen Perspektive im Bereich Leadership, Innovation und Organisation u.a. auf den Gebieten Auswahl und Beurteilung von Führungskräften, strategische Führung, Führung von Teams, der Rolle von Emotionen in Führungsprozessen sowie Anreizsystemen und Leistungsmessung in Hochschulen. Sie verfolgt dabei einen quantitativ-empirischen Forschungsansatz, in dem unterschiedliche Datenquellen (z.B. Laborexperimente) und Forschungsdesigns (experimentelle/korrelative Designs) zum Einsatz kommen.



WICHTIGSTE AUSZEICHNUNGEN

  • Best Practice Paper Award VHB – Verband der Hochschullehrer für Betriebswirtschaft (2010)
  • Best Paper Award NeuroPsychoEconomics Conference (2010)
  • Best Paper Award NeuroPsychoEconomics Conference (2008)
  • Nominated for Best Paper Award, VHB-Human Resources Division (2007)


Sixth Lecture: The fundamental Right to Life and Health. Legal and Ethical Reasons for Restrictions on Freedom in the Pandemic


Mi. 17.02.2021 18:15 Uhr

Das Grundrecht auf Leben und Gesundheit. Rechtliche und ethische Gründe für Freiheitsbeschränkungen in der Pandemie

Professor Dr. Dirk Heckmann

Lehrstuhl für Recht und Sicherheit der Digitalisierung, TUM School of Governance

Feb 17, 2021, 06:15 p.m

The fundamental Right to Life and Health. Legal and Ethical Reasons for Restrictions on Freedom in the Pandemic

Professor Dr. Dirk Heckmann

Chair of Law and Security in Digital Transformation


Das Grundrecht auf Leben und Gesundheit. Rechtliche und ethische Gründe für Freiheitsbeschränkungen in der Pandemie

Sind die aktuellen Freiheitsbeschränkungen im „Lockdown“ verfassungsmäßig? Welche Maßnahmen darf und muss der Staat zum Schutz von Leben und Gesundheit treffen? Der Vortrag erklärt die Rechtslage und entwickelt Ideen, wie ein „Grundrechtsschutz durch Digitalisierung“ helfen kann, die kollidierenden Grundrechte in einen verhältnismäßigen Ausgleich zu bringen.

The fundamental Right to Life and Health. Legal and Ethical Reasons for Restrictions on Freedom in the Pandemic

Are the current restrictions on freedom in the "lockdown" constitutional? What measures may and must the state take to protect life and health? The lecture explains the legal situation and develops ideas on how a "protection of fundamental rights through digitalisation" can help to bring the conflicting fundamental rights into a proportionate balance.


Professor Dirk Heckmann

Prof. Dr. Dirk Heckmann ist seit Oktober 2019 Inhaber des neu errichteten Lehrstuhls für Recht und Sicherheit der Digitalisierung und seit Juni 2020 Direktor des TUM Center for Digital Public Services an der Technischen Universität München. Von 1996-2019 war er zuvor Inhaber des Lehrstuhls für Öffentliches Recht, Sicherheitsrecht und Internetrecht an der Universität Passau. 2003 wurde er zum nebenamtlichen Verfassungsrichter am Bayerischen Verfassungsgerichtshof gewählt, 2007 in den Expertenkreis des Nationalen IT-Gipfels der Bundeskanzlerin und 2018 in die Datenethikkommission der Bundesregierung berufen. Seit 2018 ist er zudem Direktor am Bayerischen Forschungsinstitut für Digitale Transformation bidt. Seine Forschungsschwerpunkte liegen in den Bereichen E-Government, Datenschutzrecht, IT-Sicherheitsrecht, Digitale Bildung und E-Health.






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Seventh Lecture: COVID-19: Pandemics in Global Health


Mi. 24.02.2021 18:15 Uhr

COVID-19: Pandemien in der Globalen Gesundheit

Prof. Dr. med. Andrea Winkler

Ko-Direktorin des Center for Global Health der Technischen Universität München

Prof. Dr. med. Clarissa Prazeres da Costa

Ko-Direktorin des Center for Global Health der Technischen Universität München


Feb 24, 2021, 06:15 p.m.

COVID-19: Pandemics in Global Health

Prof. Dr. med. Andrea Winkler

Co-Director of the Center for Global Health of the Technical University of Munich

Prof. Dr. med. Clarissa Prazeres da Costa

Co-Director of the Center for Global Health of the Technical University of Munich



COVID-19: Pandemics in Global Health

The COVID-19 pandemic has brought the concept of Global Health into public focus. Until now, there was little interest in the disease burden and health care systems of other countries especially in those of the Global South. However, global health challenges are now anxiously recognized by the public at large. We are reminded of the Ebola virus outbreak 2013–2016 in West Africa, which thanks to the heroic efforts of many global health actors could be contained. During the current COVID-19 pandemic at the latest, lessons learned and best practice approaches designed by the Global Health community need to be implemented to save us from such crisis in the future.

In this webinar, we will introduce the concept of Global Health and how it is currently implemented by measures taken against COVID-19 by the global community represented by international organizations such as the World Health Organization (WHO). We will furthermore discuss how this concept has found its way into German academia, politics, and the public and how this is currently driven forward. Together with two panelists, we will gain more insight into the COVID-19 development in the Global South, the search for its origins, and the role of the WHO during this past year since the outbreak in China.  


Professor Andrea Winkler MD, PhD

Professor Andrea Sylvia Winkler is a specialist neurologist, a senior researcher, and the Co-Director of the Center for Global Health at the Technical University of Munich. She is also the Founding Director (now deputy director) of the Centre for Global Health at the University of Oslo, where she holds a full professorship in Global Health. Prof. Winkler has almost 20 years of experience with both clinical work and research in countries of sub-Saharan Africa. Her special interest lies with poverty-related neglected diseases (neglected tropical diseases) of the infectious as well as non-infectious nature, global neurology/mental health, One Health, global digital health, and social sciences in Global Health. She had/has leading roles in various large-scale multidisciplinary health consortia in sub-Saharan Africa funded by the German Research Foundation, the Bill and Melinda Gates Foundation, the Norwegian Research Council, and the Germany Federal Ministry of Education and Research, among others. She chairs The Lancet One Health Commission (together with Dr. John Amuasi, KCCR, Ghana) with offices in Germany, Ghana, and Norway. Together with colleagues she recently founded two research coalitions, The COVID-19 One Health Research Coalition and The Global COVID-19 Neuro Research Coalition, both calls were published in The Lancet and in The Lancet Neurology.


Professor Clarissa Prazeres da Costa MD

Professor Prazeres da Costa is a consultant medical microbiologist, immunologist, and infectious disease specialist, long-term lecturer, co-founder, and co-director of the Center for Global Health at the Technical University of Munich (TUM). For 17 years, she heads the research group “Infection and Immunity in Global Health” as well as the diagnostic parasitology department and teaching unit at the Institute of Medical Microbiology, Immunology, and Hygiene at TUM. Her scientific interests focus on basic immunological aspects of host-parasite interactions of zoonotic and neglected tropical diseases (NTD) and type 2 immune disorders such as allergies in relation to maternal and child health involving molecular studies, experimental models, and large-scale clinical trials in Africa. Her Global Health activities range from novel technologies, antimicrobial resistance (AMR) to Women’s Health. Her research is funded, amongst others, by the German Research Foundation (DFG) including large-scale consortia (SFB), Alexander-von-Humboldt-Foundation, and by the Germany Ministry of Education and Research (BMBF). Since March 2020 she is a member of the COVID-19 Expert Team at the Technical University Hospital (Klinikum rechts der Isar).




John Amuasi

Dr. Amuasi lectures at the Kwame Nkrumah University of Science and Technology (KNUST), where he is based at the Global Health Department of the School of Public Health and is head of the Department of Community Health at the School of Medicine and Dentistry. Dr. Amuasi is also Group Leader of the Global Health and Infectious Diseases Research Group at the Kumasi Center for Collaborative Research in Tropical Medicine (KCCR), which hosts the Secretariat of the African Research Network for Neglected Tropical Diseases (ARNTD) of which he is the Executive Director. Dr. Amuasi trained as a physician at the KNUST School of Medical Sciences and later graduated from the University of Minnesota School of Public Health, USA, with post-graduate degrees terminating in a Ph.D. in Health Research and Policy. He also served as head of the R&D Unit at the 1,200-bed Komfo Anokye Teaching Hospital in Kumasi, Ghana for 3 years from 2007-2010. Dr. Amuasi has consulted for several international organizations and is passionate about research that focuses on improving health systems, services, and outcomes, including policy analyses using both primary and secondary data in low and middle-income countries. His research currently involves field epidemiologic studies on malaria, snakebite, and other neglected tropical diseases. Dr. Amuasi also co-chairs the Lancet One Health Commission and is at the forefront of global efforts towards addressing emerging and re-emerging infectious diseases. He serves as an Executive Committee member of the African Coalition for Epidemic Research, Response, and Training (ALERRT). Through ALERRT at KCCR, Dr. Amuasi is coordinating the setup of research on the clinical characterization of COVID-19 in Africa.



Fabian Leendertz

The scientific focus of Dr. Florian Leendertz is on understanding the "where", "how", and "why" of microorganism transfer from one species to another, while a central aim is also to elucidate the importance of pathogens and microorganisms for animal populations. To address these questions, he has worked on viruses, bacteria (pathogens as well as the broader microbiome), parasites, and more recently also bacteriophages. Each project builds on a One Health framework, including both data on the host (e.g., behavior, ecology, evolutionary history) and the environment that surrounds. His research focuses primarily on the tropics of Africa, areas that present a high potential for the emergence of novel zoonotic diseases due to their high biodiversity, intensive human-animal contact rates, and significant ecological and socioecological changes and gradients. In addition to this scientific focus, the building of long-term cooperation with African partners and the building of international networks are key to his research framework; for all work in the field, regional partners are involved in the planning and implementation of the project, and wherever possible also in lab work, analysis, and the dissemination of results. www.leendertz-lab.org




Faith Osier

Faith Osier trained as a pediatrician in Kenya specialized in immunology in Liverpool and obtained a Ph.D. from the Open University in the UK. She is currently the Executive Director of the IAVI Human Immunology Laboratory (HIL) at Imperial College London. Her work in malaria vaccine development focuses on vaccine candidate discovery, the identification of correlates of protection, and the mechanisms that underpin protective immunity. Her vision is to ‘Make Malaria History’ through vaccination. She also aims to inspire and support the next generation of African scientists to provide the solutions that the continent urgently needs. Her work has led to international honors and prizes, including the Royal Society Pfizer Prize, the Sofja Kovalevskaja Award, and a UKRI African Research Leader Award. She is a TED Fellow, an EDCTP Senior Fellow, and an official #TOGETHERBAND Ambassador for the United Nations Global Goal 3. She is the current President of the International Union of Immunological Societies (IUIS) and serves on multiple international funding and expert panels.






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